Page 79 - Aussie Magazine - 2024 Issue 3
P. 79

Now back to the                    Mc means “hidden”, “ghost”        or the Mc allele. Breeders
            issue of genetic                   and “phantom” Merle. That         based their information on
            diversity.                         their Mc dog could possibly       breeding results of litters
                                               breed the same as a Merle and
                                                                                 produced. Now that we have
                                               may produce impaired Double       the technology available for
                                               Merle offspring when bred to      the accurate testing of Merle’s
            There are currently 16 labs        another visible Merle dog.        poly-A tail we are aware of
            offering Merle testing. A                                            just how common a result of
            full list is available at this     The following information is      Mc - 200 - 230 bp is at an
            link - www.merle-sine-             taken from Google search -        average of approximately
            insertion-from-mc-mh.com/          "Many solid dogs are actually     38%. What if 38% of all
            labs-offering-merletesting         cryptic or phantom merles and     phenotypically solid dogs
            Five of these labs are offering    can produce both Merle and        were removed from breeding
            the new high resolution testing    double merles. A cryptic ghost    programs based exclusive on
            method but only two of these       or phantom Merle is a dog         a result of Mc?
            are offering base pair numbers,    which phenotypically appears
            mosaic results and up-to-date      to be a non-merle or very faint   Genetic diversity would be
            information in regard to the       patches of Merle that can go      greatly impacted. I have
            Mc allele. Eleven labs are still   unnoticed. Animals that do not    already seen dogs tested
            using the old method of testing    present the Merle phenotype       as Mc spayed/neutered and
            and only two are offering          may possess the Merle             removed from the genetic pool
            correct genetic information        genotype and subsequently         either based on information
            in regard to Mc. That leaves       produce Merle offspring. These    the owner found through an
            us with 12 labs that have old      dogs are known as cryptic         internet search or following
            outdated and inaccurate non        Merles." Scary stuff indeed!!     the advice of labs stating
            genetic information on their                                         not to breed Mc to M for the
            websites. Along with literally     Information such as this has      fear of producing Double
            hundreds of websites who           not been overly detrimental       Merle offspring and passing
            repeat this information over       in the past when there was        this “unsafe” Mc allele to the
            and over again, as well as old     really no reliable test for Merle   future generation.
            information cited from old
            Merle studies, some that were
            based only on phenotype and
            not on genetic testing. Any
            Google search for “Cryptic
            Merle” will result in pages
            and pages of websites using
            the old catch-all, convoluted
            and non-genetic meaning of
            the term. I have seen very
            limited progress over the
            past year from most labs and
            breed websites to update
            their Merle information. The
            damage being done could be
            disastrous to many breeds as
            dogs testing as Mc - 230 bp
            and under are neutered/spayed
            and removed from breeding
            programs due to the fear that



                                                                            A Worldwide Magazine for the Aussie  •  Issue 3/2024  |  79
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