Page 103 - Aussie Magazine - 2024 Issue 3
P. 103

The ASHGI Cancer Survey,
                                                                                 conducted in 2006-7 made
                                                                                 it clear that the Australian
                                                                                 Shepherd has two inherited
                                                                                 cancers: Hemangiosarcoma
                                                                                 and lymphoma. In addition,
                                                                                 both cancers tend to occur
                                                                                 in the same families,
                                                                                 indicating that they may
                                                                                 have something in common
                                                                                 genetically. This knowledge
                                                                                 means that breeders can
                                                                                 minimize risk of producing
                                                                                 dogs that will develop these
                                                                                 cancers by making note of









            This process has actually
            made the dog the premier
            research animal for cancer.
            It is no surprise that the key
            researchers on the Canine
            Genome Project, completed
            in 2005, were also studying
            human cancer. The roughly
            400 modern dog breeds
            represent distinct subsets
            of canine gene variants. A
            gene version important to
            a particular cancer may be
            found in only a few of those
            400 breeds, and may be
            common in only one or two.
            Familial patterns of cancer
            are very difficult to trace in
            human populations, but dog
            breeds with their closed gene
            pools and studbook records
            are ideal for the purpose.

            The apparent increase in           to puzzle out what was            cases and avoiding breedings
            cancers among younger              happening. I told Dr.             where both parents have the
            Aussies in conjunction with        Armstrong I felt our breed        same cancer in their recent
            increased coefficients of          ought to be studied more          family background. ASHGI
            inbreeding concerned me.           closely for cancer, but his       has included these cancers in
            I knew the longevity study         untimely death brought an         its pedigree analysis service
            data was not sufficient            end to his work.                  since 2008.



                                                                           A Worldwide Magazine for the Aussie  •  Issue 3/2024  |  103
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